- Sildenafil citrate or Viagra is the most commonly used drug. It also treats other male sexual dysfunction. The salt form of the medicine is Sildenafil citrate. It is generally used to increase blood flow to the penis to help a man maintain it for increased sexual activity.
- Sildenafil Citrate Tablets (Sildenafil Citrate 50-100mg Tablets) or Viagra is the most commonly used drug for the treatment of erectile dysfunction.
What is sildenafil citrate?
- Anti-impotence drug.
- This medicine has proved to be very useful in the treatment of impotence due to erectile dysfunction (ED).
- Chemically it is dihydromethyl, 7 oxo, 3 propyls, 1 H pyrazolyl,oxos3 dipropylsdine, pyrazolylphenyl sulfonyl, 4 methyl piperazine citrate.
- This drug is obtained and synthesized from a plant.
- This drug enhances the activity of cyclic guanosine monophosphate (cGMP) by affecting the actions of 5 phosphodiesterases (5 PDE).
- Phosphodiesterases work only at the time of sexual stimulation.
- Nitric oxide N2 O2 (NO) is generally released in the corpus cavernosum during sexual arousal in men. Due to this the level of NO increases significantly there.
- The increased amount of NO activates an enzyme guanylate cyclase there. Which increases the level of cyclic guanosyl monophosphate (cGMP). c Increased levels of GMP cause relaxation of smooth muscles in the corpus cavernosum. Due to this the blood flow in this increases. Which is perfect for the meeting.
- When a male consumes Sildenafil Citra ate drug. So it does not do any work under normal conditions.
- At the time of sexual arousal, this drug acts on phosphodiesterase in the corpus cavernosum.
- While affecting (c) GMP) increases the level. NO is liberated there in large quantities. and increased blood flow to the corpus cavernosum. As a result male’s penis (due to erectile dysfunction) | becomes straight and hard. that he can enjoy sexual intercourse.
Uses of Sildenafil Citrate.
- Impotence due to erectile dysfunction.
Availability.
- Tablets.
When to avoid sildenafil citrate?
- Hypersensitivity,
- Patients on nitrate drugs,
- Women, children, and newborn babies.
Precautions while taking Sildenafil citrate.
- Do not take medicine during pregnancy, lactation, and childhood.
- There is no problem with using medicine in old age.
- No other aphrodisiac should be taken with this medicine.
- Give this medicine very carefully to patients with both high blood pressure and low blood pressure.
- Give this medicine to the GENITO-URINARY SYSTEM very carefully.
- Give the medicine care to patients who have had a heart attack within the last 6 months.
- It is best not to use the medicine ZE in eye disorders.
- Use caution in drug use in ulcer patients.
- Be careful in giving medicine to patients with leukemia, sickle cell, anemia, and multiple myeloma.
- Give this medicine with extreme caution in patients having a structural or anatomical disorder of the penis.
- Use medicine carefully for liver and kidney disorders.
Side-effects of sildenafil citrate.
- Nausea,
- Stomach pain and burning,
- feeling heavy in the stomach,
- Headache,
- Diarrhea
- Eye disorders,
- Dizziness,
- Nasal congestion,
- Skin rashes,
- Change in blood pressure (Variation in B. P.),
- Bleeding from an ulcer,
- Flushing of the face,
- Mandagni (Dyspepsia).
Drug interactions with sildenafil citrate.
- When given with Rifampicin, both the level of sildenafil in the blood and the effect of the drug are reduced.
- The excretion of sildenafil citrate is reduced when taken with Erythromycin, Ketoconazole, Cimetidine, etc.
Substitutes of Sildenafil citrate.
- MANFORCE – MANKIND
- PENEGRA – ZYDUS
- INTAGRA – INTAS
- VIGORA – GERMAN REMEDIES
- PROGRAMMARA – Cipla
- ROCKY – Bestochem
- VISTAGRA – Cadila
- WINGORA-MEYER
- ZERECT – FDC
- ALSIGRA – ALEMBIC
Frequently asked questions about Sildenafil citrate.
Q-1: What is the Sildenafil Citrate tablet used for?
A-1: Sildenafil is used to treat men with erectile dysfunction (also known as sexual impotence). Sildenafil belongs to a group of drugs called phosphodiesterase 5 (PDE5) inhibitors. These drugs prevent an enzyme called phosphodiesterase type-5 from working too fast.
Q-2: When should I take Sildenafil Citrate?
A-2: Take sildenafil as needed before sexual activity. The best time to take sildenafil is about 1 hour before sexual activity, but you can take the medicine anytime from 4 hours to 30 minutes before sexual activity. Sildenafil should usually not be taken more often than once every 24 hours.
Q-3: Is sildenafil tablet safe?
A-3: Sildenafil is a safe and effective medicine when used as directed. Be sure to follow the tips listed below to safely use sildenafil to treat erectile dysfunction: Do not exceed the recommended dose. Sildenafil is prescribed in three common doses, ranging from 25mg to a maximum dose of 100mg.
Q-4: Can I take sildenafil daily?
A-4: The short answer is yes; You can take Viagra or its generic form, sildenafil, every day. Whether you want or need it depends. Since each person is different, you should consult a doctor about what is best for you. They can discuss the quantity and frequency.
Q-5: Can sildenafil cause harm?
A-5: Viagra can cause a prolonged erection. If left untreated, this can lead to permanent erectile dysfunction. Viagra can also cause a serious eye condition called non-arteritic anterior ischemic optic neuropathy, which can lead to permanent vision loss. However both of these side effects were rare in studies of the drug.
Q-6: For how many hours does Sildenafil remain effective?
A-6: This medicine usually starts working for erectile dysfunction within 30 minutes of taking it. It continues to work for up to 4 hours, although its action usually wanes after 2 hours.
Q-7: Does sildenafil work the first time?
A-7: Although the success rate is high, Viagra may not work the first time you take it and is not guaranteed to always work. Feeling relaxed and getting in the right frame of mind increases the chances of Viagra working. It is also important to note that Viagra will only work when you are sexually aroused.
Q-8: Can Sildenafil be taken at night?
A-8: Our data suggest that sildenafil, administered at bedtime, is effective in improving sleep-related erections in normal men, indirectly confirming that the nitric oxide pathway is important in the physiology of erections during sleep. The effect of sildenafil lasts for 8-9 hours after its consumption.
Q-9: Is sildenafil good for the heart?
A-9: It lowers pulmonary vascular resistance, improves exercise capacity, and is now an approved therapy for this condition. Heart failure (HF) patients also have pulmonary hypertension and several recent reports have shown that sildenafil improves their exercise capacity.
Q-10: How do you know that Sildenafil is working?
A-10: Viagra does not start working immediately after taking it, as the drug takes time to get absorbed into your blood. For most men, it takes about 30 minutes to feel the effects of Viagra. 12 minutes later – One study showed that some men got an erection as early as 12 minutes after taking Viagra.
Conclusion:
In conclusion, sildenafil citrate is a widely used medication for treating erectile dysfunction in men. It is important to follow the prescribed dosage and consult with a healthcare provider to minimize potential side effects. By understanding the uses, side effects, and precautions associated with sildenafil citrate, individuals can make informed decisions about their health and well-being.
Disclaimer – The information given above is to the best of our research and knowledge. But, you are advised to consult a physician before consuming the medicine.